Viagra: DURATION - 2 YEARS

The most popular drug to help men with erectile dysfunction naslazhdetsya fulfilling sex lives, may lose the effect after 2 years.
Such conclusions were made by American scientists on the basis of interviews with 150 men who took Viagra for a long period. In the early years are ahead of them a dose of 25 to 100 milligrams. Approximately 37% of using Viagra in order to achieve the same effect through 2 years have been forced to increase the dose to 50 mg. And doctors have found no link between frequency of use of the drug and caused an increase in dose.
Some of those surveyed stopped using the drug, as one Viagra does not help, while others were able to solve the problem independently, ie they recovered erection.

Death from the use of Viagra

In a world so far have died, more than 600 people who had used the drug Viagra pharmaceutical corporation Pfizer. This is stated in the Ministry of Health of Germany. At the same time, according to doctors, it can not be said that it was Viagra was the cause of these deaths. Although, as noted by Reuters, death followed soon after use of the drug. Typically, the immediate cause of death in such cases is a cardio-vascular insufficiency.

Viagra and other drugs

In the near future in the market from famous Viagra impotency can seriously substitute two new drugs. This is a Tsialise (Cialis) from Eli Lilly and the fruit of joint efforts of companies Bayer and GlaxoSmithKline, which this week was finally the name Levitra (Levitra). It is anticipated that the sale of them in the United States will start next year.

Competitors Pfizer’a do not expect an easy victory in the battle for market share. We know that only last year, in fact, in the absence of competitors the company has spent more than $ 100 million for the promotion of Viagra. Vice-president of GlaxoSmithKline, David Pernok (David Pernock) promised to do ‘anything’, to convince men to use the new tool.

Manufacturers of Levitra, the drug, formerly known under the chemical name vardenafil, and the creators Tsialisa hoped that receive permission to sell this year, but experts of the Food and Drug (FDA) gave only conditional approval, specifying the need for additional studies to confirm drug safety.

Works which would be directly compared to the various preparations of impotence, no. Each company is ready to provide materials of their own research. Reported that sexual intercourse can normally make 77 percent of volunteers who took Levitra in dose of 10 milligrams, compared with 45 percent taking placebo. Viagra has been notified to the figure of 55 per cent.

According to comments from representatives of Bayer, Levitra - the most important for the drug. His output is particularly important in connection with the ban in the year before last medication, which the company promoted as a means to combat high levels of cholesterol. They expect that new means of impotence will bring up to a billion dollars a year by 2007, of which about half of departing partners - GlaxoSmithKline.

The new name for the drug was given in this Monday. He chose the names of 700 applicants, with the help of experts from the New York Institute of brands. According to specialists, the floor is made from the French masculine pronoun, and the Latin word ‘life’. It is not known how to move product, the company may resort to the assistance of prominent people.

Medicines for impotence better than Viagra

The company “Bayer AG” has announced the first results of the third phase of clinical trials of its drug to treat impotence.

At the annual meeting of “Sexual Medicine Society of North America”, the company “Bayer” presented the first data the third phase of clinical trials, according to which the effectiveness of the drug has reached 85%. This is higher than drug Viagra - “blockbuster” the company “Pfizer”.

Viagra acts on the 82% of its male host. In tests of the drug “Vardenafil” was attended by 736 men over the age of 18 suffering from erectile dysfunction (weak or short-erection).

“Bayer” and the largest pharmaceutical companies in Europe, “GlaxoSmithKline Plc.” planning to implement a joint promotion of the drug in the world market by fall of next year. “Bayer” expects that over time, annual sales of the drug reached 900 million dollars.

“Vardenafil” an affront to Viagra, the first pill to treat impotence, appeared on the market in 1998. Perhaps, “Vardenafil” and will compete with the drug “Cialis”, designed for the treatment of impotence by “Eli Lilly & Co”.

“Cialis” must obtain permission to sell next year. Effects of all three drugs based on blocking the enzyme 5-fosfodiesterazy type, and all three drugs require sexual stimulation. However, previous clinical trials have shown that the drugs “Cialis” and “Vardenafil” act quickly and have fewer side effects than their rival Viagra.

Viagra: A NEW MILLENNIUM - THE NEW SEX?

Hair, nails, skin, muscle tone, the quality of erection … In assessing them, neither man nor woman can no longer rely on its internal sense, because the quiet whisper of nature is almost never heard of thundering revom civilization. In the mass consciousness prevail phantoms, for which the hardness of iron separated from the iron-hard penis. Well, welcome to the club, “sang the unforgettable Mel Torme …

As rightly pointed out by Marx, capitalist mode of production inevitably leads to the most simple and natural things - food, music, sex, health - ruthlessly selected by the person and returned to it in the form of goods, which must be paid for (we will not go on hunting, but in the shops, we do not touch the piano keys, but the DM musical centers, our imagination does not incite the body lovers but pornographic images in magazines, we are not under the sun rays of the sun in May, but under quartz lamps solaria). And although we want to believe that Russian people do not devour the Moloch of bourgeois civilization, the chances he маловато.

A little more political. The second half of XX century - the era of corporate capitalism with its inherent mass production and mass consumption of almost all: food, food culture, etc. In such conditions, stimulation of sophisticated demand becomes central to the survival of the economy, and marketing - the ideological pillar of the society of consumption. Only aware of it, you can more or less sensibly talk about the achievements of science and technology, for which we are urged to pay. One of these achievements - Viagra, a pleasant surprise from the pharmacy, promising earthly paradise for all the suffering. So far, however, a prescription … Well, talk at first - no, not about the recipes - on a doctor.

Unfortunately, medicine today is not so much social good, as part of the service sector and often played a dubious role of the advertising agent, helping in the formation of consumer demand for cosmetic, pharmaceutical and other products. So, visit the office of the contact addresses of vision correction is not purely a medical problem, but inevitably causes the patient to commit an act of purchase and to enter into economic relations with the specific manufacturer of contact lenses. In addition, the cosmetic-pharmaceutical industry supports the sales of the extreme fragility of the human health. The whole ideology of manufacturers of cosmetics and kvazilekarstvennyh means, nutritional supplements and vitamins is that the person may remain alive only through their product continuously and indefinitely to “improve” their condition. And that he did not become bored in the pursuit of ghosts, using the means-tested: increased range, update the concepts of “healthy lifestyle”. Let’s be careful successive other campaigns for and against sunburn, inspiriruemye manufacturers of cosmetics. Alas, the poor protested reasonable consumer: “I do not want the choice was more, I want the goods have been better” - inevitably sinks to the advertising “noise” that accompanies the emergence of new products on the market.

According to its economic nature “Viagra” - such as the fruit of the pharmaceutical industry, as a toothpaste with fluoride or multivitamins. And in the market competition, it has a much more interesting features than with the direct violations of blood flow in the small pelvis. The potential market for Viagra from the beginning split into two unequal segments. First - small - are men suffering from impotence real. Second - most plodonosny - consists of a vast number of individuals, concerned not so much the quality of their erection (they were satisfied with it), but their number per unit time. Whatever modest nor doctors had prescribed “norm”, these men were not questioned their views on healthy sexuality, and earnestly insisted on the need to make love as often as they want (Talk about the “want” section below). If the “Viagra” will be sold without a prescription (by which there are no contraindications) or on the black market, these men will take it in doses, and horses with full confidence in the correctness. It is about this part of the potential market is now played major ideological battle in the center of which is not impotence, as such, but the meaning, which is invested in it. The advent of Viagra has a new urgency the question of what is the norm and that there is a pathology of sexual life. This opens a wide field for a variety of speculations: as in politics, raising children, and artistic taste, the evaluation of sexuality and sexual health rule double (triple, quadruple, etc.) standard. On the one hand, there is a scientific, in this case - the medical definition of sexual norms, which is given to any medical encyclopedia.

Based on it, the doctors tell us that such impotence, and, guided by these considerations, issue a prescription for “Viagra” or are denied itself. So the definition of a medical doctor becomes a lever of power over the patient, although the medicine is not an authoritative source of judgments about their sexual lives. Quite the contrary: the medical understanding of sexuality is in constant evolution, which is more akin to chaos. So, yesterday Homosexuality was considered almost a somatic disease today - variant rules. What to talk about such delicate and subjective matter, as the frequency and quality of erection. Here science leaves too wide a field for interpretation.

And helpless statement sexologists that individual norm “can vary widely, instead of confidence caused the patient only neurosis. Generally speaking, any sexologist confirm that the physician in this situation - the last man, whose suffering will ask council. For our contemporary there are many other, more accessible and authoritative sources from which it draws its ideas about the normal or desired in the sexual sphere, reaffirming or disproving their own suspicions and fears.

In thinking about their sexual behavior is guided by a wide variety of reasons, most of which are under constant pressure from the outside (of the received education up to role models, absorbed through the media). The most severe dictator and the real Lord of doom is, perhaps, the mass culture. And this despite the fact that she does not claim, as opposed to a doctor at the role of authority and not a single answer to the question of what is normal sexual behavior. And indeed, the majority as templates on which vymeryaetsya own “I”, choose that which is constantly investing in the head, then, for what you do not need to reach the book shelf.

Non-critical learning the myths and stereotypes created by modern culture, we cease to distinguish the line between reality and fiction, not realizing that the horse’s potency pornoaktera - the fruit of video and nothing more. And is equal to him in his actions as meaningless as to imitate Betmenu. But not only the culture - the whole structure of modern life nothing less than a man pushed to the critical evaluation of themselves and their potency. And while for the rights of “ordinary women” - even as a marketing trick - in the West have become intervene some major cosmetic players, the market (we are referring to the campaign of one of the firms under the motto: “There are only eight women who look like top models. What do the rest? “), a man all the relentless scorer images and verbal formulas, glorified the cult of youth, virilnosti, aggressive sexuality. When that had no demographic reason: the population of developed countries is aging and wait for the growth of secondary sexual acts per capita naive. However, with the advent of Viagra the situation could change. At least the man will now be able to guarantee the “mechanical” part of an act of love … And what about the fair sex? We can not say that women’s camp shows unity. However, before the apparent rift too far.

For feminists “Viagra” is probably the strongest irritant. For them, a new drug - one more instrument of exploitation, which gives a new degree of freedom of a man and a woman obdelyayuschy automatically. Examples same reception Viagra by ladies in an attempt to squeeze out more pleasure from the erotic situation (not of men, note) would be probably regarded as another desperate attempt to break with its “subordinate role in a patriarchal society-oriented” and to show at least some initiative. For neemansipirovannoy female “Viagra” also means a clear change in the nature of her sexual life, though … Who is the risk of making general conclusions about the nature of these changes? Indeed, on the quality of sex between men and women, as there was no consent or not. Known: a man, in principle, can be satisfied with sex, orgasm ended (the orgasm, of course).

For women are much more complicated. Perhaps, for clinical impotent wife is the opportunity to resume a full sex life can be a source of satisfaction. For partners, the relatively healthy person who is trying to get from the “Viagra” is not what rasschedrilas nature, primitive triumph over another erection can be a source of irritation. For the straightforwardness of a partner, convinced that a good erection sufficient to make happy a woman in bed, the most frequent cause of women’s dissatisfaction and cruel disappointments … All told, to some extent, a generalization. What happens with Viagra on a separate - in this case, the domestic market, hard to say. Its success or failure will be linked, we must think, not so much to pay the average Russian man, but his world and self. What can I say about this now?

Russian people say, prone to self, he has a “soul”, is still unclear strangers. From this perspective, the prospects for “Viagra” questionable. On the other hand, being brought up in the rarefied environment and colorless Soviet media, Russian is often quite vulnerable to aggressive manners of modern mass culture. And here for the “blue pill” offered some opportunities. Thus, in the first approximation, the situation looks like this: for those whose Bible has already become Russian version of glossy magazines (constant themes - a flat abdominal press, a healthy diet, techniques of sex), prichaschenie to Viagra inevitable. Those who still read Dostoyevsky or “truth” and seeks the truth within themselves, the emergence of “Viagra” can not miss. However, the last judge here is simply Rossiyanka. Although the choice, seeing God, is not: a lot of sex or a little sex, happiness, it is still “difficult” to achieve a destiny of great price. And on what scale dry tap falls pill Viagra - we have not been to predict …

What we know about “Viagra”?

* “Viagra” - this is medicine for the treatment of impotence.
* “Viagra” improves blood circulation in the pelvic area and makes erection longer and sustained (from 30 minutes to 4 hours depending on dose).
* “Viagra” should be taken an hour before sexual intercourse. Before turning to Viagra, it is necessary to ascertain the cause of impotence.
* “Viagra helps in cases when it comes to cardiovascular problems, age-related changes, psychogenic disorders. “Viagra” in a position to help people with diabetes in the development of impotence against the background of beginning of vascular complications (angiopathy). At later stages of the disease “Viagra” will not help.
* If the atherosclerotic changes in the direct cavernous bodies of the penis, “Viagra” powerless.
* When psychogenic disorders use “Viagra” be combined with psychological assistance.
* “Viagra” will not help with the irregularities develop in the body of sex hormones. Contraindications: heart disease, including coronary, violations of the heart rate, hypertension, hypotension, use of alcohol. Absolutely no combination of Viagra with nitroglycerin and other nitropreparatami (sustak, nitrong, nitrosorbid).
* Erythromycin and tsimetidin reinforce the effect of “Viagra”. This means that the erection may become so long that a desired turn into unbearable.
* Side effects: deterioration of vision or distortion of vision (all around becomes blue), bowel disorders, headaches and muscle pain, runny nose.
* The use of “Viagra” healthy people as a stimulant can have sad consequences, up to a full impotence (which does a drug!). Do not experiment with Viagra and young people not reached puberty.
* In the few months that the drug is sold in America, recorded dozens of deaths that are associated with “Viagra”.
* The addiction to the drug Viagra is not, and psychological.
“Viagra” affects the potency, but awakens the libido, ie, sexual attraction. Before the financial crisis was planned, that in Russia Viagra will go on sale in November this year and will be sold only on prescription. Branded packaging imply a hologram and a special way prokleennye valves, each tablet in a plastic bag.

Prescription drugs may be of any physician with a personal stamp. There are no regulations regarding the Health Ministry that it should make only a specialist (andrologist, for example) are not developed.
For your own safety, you need only buy the drug at the pharmacy.

What we do not know about “Viagra”?

* Who will formulate the indications and contraindications for “Viagra” more clearly?
* How serious will be trained doctors? And if they pass it at all?
* Will orthopedist or a dentist from the temptation to prescribe a cure for impotence friend, who asked him about it?
* Whether or not “any physician with a personal seal, competently assess whether” Viagra “- with all its ambiguity - is shown a particular patient?
* Is it true that one pill will cost 7-10 dollars - like in America?
* Is protected from forgery product packaging?
* What long-term consequences of regular and long-term taking the medication? For example, could it affect our offspring?

Viagra And Women

Even before Viagra really “went on-line marketing space, can easily anticipate: the drug, developed by men and for men, of course, be in demand and women. Why? Difficult to identify the main reason - for the reasonably long, and they are all very skillfully intertwined with each other.

Perhaps the major role played by rage in this century, the spirit of emancipation - it Zadornov provokes an excellent half of humanity to the “development” almost all the expensive and high-tech “toys”, men selfishly think only for yourself, loved ones. A selfish in this regard the sons of Adam and really does not hold. Including - and in the medical field. The amounts that are invested in projects designed to deal with “typical male” problem - say, baldness or erectile dysfunction - can impress any man. While over the past decade, all medical science had not made one, and any significant step to victory over a very common problem, as premenstrual syndrome. As you know, they are only ladies, but because a strong half of mankind, have seized all the dominant heights in science and farmindustrii, all as the “nedosug” take this matter up. Insulting? You bet! And then another man, having no definite “try out” the blue pill, began to dismiss rumors of miraculous properties of a new drug, attributing to him directly, the effects are fantastic. For the modern woman, not devoid of adventure - it is a direct challenge. “A lodge here Lyapkin-Tyapkin …” - And thousands of the beautiful sex went for a recipe for Viagra … the World Wide Web.

However, online Viagra drink - it is the realities of life overseas, as tamoshnyaya sensitivity does not sell drugs without prescriptions. We have it - as much simpler: the prescription form, in most cases soydut bright paper, called bank note. And the great American privacy in Russia today blyudetsya steeper than that of “them” - no one would ask - why would a young girl medicine oriented to the needs of men “over 50″.

The result of all these superlative degrees of freedom will not be slow to occur in the Fatherland through a few months after the appearance of Viagra on the U.S. market - and the result is, of course, also quite predictable. If a lady, named Express-poll site Doktor.Ru “Katen’ka, succinctly commented on his experience with Viagra” as “Wow … this is just cool …”, then a popular women’s magazine Cosmopolitan broke an entire article to the intriguing title “I tried Viagra.” In this opus, subject to all laws of the genre “tells about the impact of such power of blue pills, which can be compared perhaps only with the full force of the impact of the moon on the reverse. From the article naturally to the conclusion that taking Viagra gives a woman vsesokrushayuschim libidonoznym pressure, just makes it a besnuyuschuyusya nymphs, and even - for some reason it gives some typical characteristics of male sexual physiology. Against this background, in the text warnings look like something hollow.

Such comments can “punish” the top ten experts: Is sildenafil, tritely fosfodiesterazu-5 inhibition in the tissues of the penis and thus improves the impact of nitric oxide at the level of cyclic guanozinmonofosfata, except for natural relaxation of smooth muscle fibers may also stimulate some mysterious brain centers? It is easier to forgive if the description of biochemical steps Viagra caused your lung irritation, but in terms of pharmacodynamics sildenafila, the effects described in the “Cosmo”, is almost impossible to explain. But just remember a scene from “Taming stropivogo” where the hero in the performance of A. Chellentano, bought heroin in the performance of O. Muti samokrutkoy with supposedly grass, dropped manifestnoe bliss Ladies phrase: “And I did not know that a simple chicory has the effect “.

Autosuggestion (autosuggestiya) - a powerful thing. Especially if the object is a man of nature “inspires.” And if the “stimulus” - to an extraordinary, one might say, legendary. Yes, and yet its value is that, compared with the “just relax” even gold and platinum - the way, a kilogram of Viagra is as much - more than 200 000 dollars! So in this respect, sensation does not seem to be: sildenafil should never raze is not suitable for the company, which has long been prescribed Spanish fly, cocaine, dry snake blood and other “love exotics.”
However, not all too bad in “The Kingdom of Denmark - Viagra, and it is still able to play any positive role in the treatment of sexual dysfunction in women. At least, the reason for this is: sildenafilom caused by the inflow of blood to the genitals of women could benefit the two major factors affecting the quality of women’s sexual sensations - lubrikatsii genitals and clitoris erection. Lack lubrikatsii (wetting of the reproductive tract) during coitus leads to what has been termed “dry sex” - say, the last is very popular among the African people, well yes, and … OK, but the majority of women from other ethnic groups were of the opinion that this thing malopriyatnaya. Dr. Arthur L. Burnett of Johns Hopkins University, and his colleagues cautiously say that Viagra could help here. As for the “erection” clitoris, it shall in no small measure upon the possibility of a woman of so-called klitoralnogo orgasm - and thus determine the strength of physical experiences during sexual intercourse. Panel doctor Burnett believes that there sildenafil may be useful - in fact the mechanism of erection clitoris to a certain extent, it reminds erection of the penis of men.

Note that these views are worth listening very attentively: Dr. Burnett - a very well-known specialist, to the same - one of those who stood “in the cradle of” Viagra. In 1992, he and his colleagues drew attention to the medical community to the role of nitric oxide in the origin of erectile dysfunction in men. The publication in the journal Science, where scientists believe the statement that gave rise to a steep turn in the fate of future Viagra - because on the original intent of the developers of sildenafil, the prototype had to fight not with impotence, but … ischemic heart disease. And as such, the product entrusted to him the expectations are not justified. But the improvement of erection observed in patients during clinical trials, seen as weird side effect sildenafila. Until the above-mentioned publications. So that now is a Viagra - a considerable achievement Baltimore researcher.

However, the same doctor Burnett does not recommend routine use Viagra for women - the risk of adverse and even dangerous side effects of the drug can not be justified by any hypothetical “testimony” of his reception. Today in Baltimore to continue to closely study the effectiveness of therapy sildenafila female sexual dysfunction - evaluated the qualitative changes that spanned dosage and mode of introduction of the drug. The results of this work, no doubt, will be published. And we, of course, try to inform our readers about them. According to the “old (but very good) song on the main” - “We should just learn to wait, you must be calm and stubborn …”. And yet Viagra without a prescription to take is still not worth it.

Aphorism

Hurry to apply the new tool, as it all helps!

Viagra - the triumph of the blue pill

In March 1998, the FDA formally approved one of the latest pharmaceutical giant Pfizer Inc. - Tablets commercial name Viagra. The experts agree - the appearance of Viagra has marked the transition to a qualitatively new level of treatment of erectile dysfunction in men.

The little blue pill has become yet another gift of scientific and technological revolution conferred upon the altar of consumption - because of the opening behind the development of Viagra, three American scientists (R. Ferchgott, L. Ignarro and F. Myurad) in the same way in 1998, received the Nobel Prize for medicine and physiology! Two words in defense of scientists. Award received for many years and the successful study of the role of nitric oxide in the circulatory system, rather than the development of Viagra, as some local magazines. For all the relevance of the problem of impotence - for the Nobel Prize Viagra still has not drawn. ”

But the newly “amplifier erection” immediately established itself seriously in the market of medicines. Only in the United States for only five months, it was issued more than 3 000 000 prescriptions for this drug! In the retail cost of one pill in the $ 15 - $ 20 there can be no doubt - Viagra is a breakthrough not only in the therapy of impotence, but also in the pharmaceutical business.

Once America and Europe, the magic blue pill invaded the markets of Asia, and seems to have a good chance of winning. But in the Far East, almost every man considers himself an independent expert in the field and the potency of art “control of erection.” Viagra to be a brutal war with the present (not grown in Odessa), Tibetan herbs and roots, serpentine blood and other exotic animal extracts, ancient cults, terrible prejudice and the brainchild of high technology. The recent call took only Japanese erectile panacea Love Jet, and then as the uncertain, and only in the domestic market of Japan. It seems, Pfizer-ovsky blitzkrieg will look spectacular even than the notorious “browser war” between Microsoft and Netscape. We will return to this subject.

The fact that Viagra is a lot written in the popular press. Recall only that this “name” of the drug - sildenafila citrate, it is introduced into the body through ingestion banal (and more recently - and a simple injection spreya sildenafila directly into the nasal passages, as any “nazola).

The mechanism of action of the simple (like all brilliant): With the help of nitric oxide in the penis enhancing blood flow occurs. This provides a nearly physiological erection without anguish. It is very effective: 7 out of every 10 men who have had problems with potency, the most successfully resolved these problems by using Viagra! In doing so, managed not only to reach a persistent and prolonged erection, but also improve the quality of sexual sensations and emotions! Incidentally, this information and its “people’s Echo” persuaded not only to healthy men, but also the most advanced representatives of “weak sex” to experiment with Viagra. Not so long ago, a popular women’s magazine posted an article “I have tried Viagra!”, Which apart from pharmacological effects sildenafila easy to learn and psychogenic effects - ie the effect of self (of course it caused not by the drug, and advertising “noise” around onogo). Clearly, this op would fuel the already neslaby excitement surrounding the blue pill.

All would be nothing, but now Viagra in fact - not a symbol of layfstayla, a drug that has side effects, sometimes very serious. Mechanism of action sildenafila based on the ruthless suppression of the specific human proteins - mainly fosfodiesterazy 5. But now this last time and is responsible for side effects of Viagra is not without the help of which have already parted with life nearly 7 dozen. Unwanted effects of drugs may include lowering blood pressure and headaches, disturbance of color vision, etc. has already been described zhizneugrozhayuschego case of pulmonary complications. With great care should be taken this drug for patients with diseases of cardiovascular system, liver and kidneys. It can not be combined with Viagra protivoishemicheskimi nitrate - nitroglycerin, sustakom, nitrongom etc. There is still a mass of points that should be discussed with a good doctor before taking Viagra for.

In general, Viagra - are not vitamin supplements, and to prescribe her own in most cases should not be, because it may be unsafe. American experts have insisted on only leave this prescription drug and a large number of warning labels and notes on the package. There can be no doubt that law-abiding capitalists do so and all will be done. But on us - there is no such confidence. Viagra has had on the domestic drug market, are sold without prescriptions, and, judging by the comments of pharmacists, is in demand. Form this azhiotazhny demand normal process of aging citizens, the economic crisis, official and unofficial advertising rumors and more … Tax Police (judging by her last year’s spot). One can only optimistically hope that our naturalists both sexes not affected in their experiments with Viagra.

By the way, Pfizer has made that have not yet managed to anyone - was able to measure in monetary terms is truly priceless as the erection phenomenon. At first glance, the cost is low - $ 18-20. However, the lack of demand for Viagra to maintain a normal sex life “saves” the man, depending on its activity, from $ 2000 to $ 5000 per year! As with the current exchange rate is very good.

Bravo, Pfizer!

Anecdote:

- Doctor, ginseng root may help to sexual impotence?
- Can only bind stronger.

Medicines

If a reception gipolipidemicheskih products you note the reduction of potency, in any case not to interrupt their own treatment. Discuss this issue with a doctor who will help you to find other drugs. Administration of this site is not responsible for the abolition of autocratic medical treatment.

The drugs used to reduce the level of lipids in the blood (antiateroskleroticheskie, gipolipidemicheskie drugs) typically used in combination with other drugs, which is quite difficult to confirm their effect on potency. Nevertheless, we show that klofibrat lead to erectile dysfunction (impotence) in almost 14% of patients

Mechanism of action gipolipidemicheskih on the potency of drugs is associated with declining availability of cholesterol for the synthesis of testosterone. In addition there accelerated decommissioning androgens.

New gipolipidemicheskie drugs - inhibitors of 3-hydroxy-3-methyl glyutar Coenzyme A reductase (lovastatin, pravastatin, simvastatin) - lead to erectile dysfunction (impotence) for reasons not entirely clear. Dose reduction is accompanied by the elimination of adverse manifestations.

Klofibrat:

Shape of release: capsules.

What is Klofibrat: preparation, correcting lipid metabolism. Reduces elevated levels of lipids in the plasma by reducing the fraction LPONP and LPOP saturated triglycerides. In the liver klofibrat increases metabolism, inhibits the release of hepatic lipoproteins (in particular LPONP), activates lipoproteinlipazu in adipose tissue and increases the excretion of neutral sterols in faeces. Klofibrat increase cholesterol in bile, and improves tolerance to glucose, lowers blood viscosity.

Indications: giperlipoproteinemiya III, IV, V and possibly IIb types of non-correction of diet and physical activity. Diabetic retinopathy ekssudativnaya and hyperlipidaemia caused by diabetes. Ksantomatoz. Stable improvement of fibrinogen associated with atherosclerosis.

How should I take: daily dose - 20-30 mg / kg, the multiplicity of the reception - 2-3 times / day. preferably after meals. The minimum duration of a continuous course of treatment - 3 months.

Side effects: may: gastrointestinal disorders (nausea, vomiting, bowel diskineziya); itchy skin, rash, pain in the muscles (myositis-type), muscle weakness (often in the lower leg), drowsiness, dizziness, headaches. A long application of the drug may develop intrahepatic cholestasis, education gallstones in the gall bladder and biliary tract disease exacerbation zhelchnokamennoy. Seldom in the long-term use of drugs - impotence, alopecia, transient increase of transaminases, increase in body mass due to the delay of fluid in the body.

What should I avoid while taking Klofibrat: breach of terms of liver function and / or kidneys; zhelchnokamennaya disease; gipoproteinemiya, pregnancy, lactation.

Cautions: Not recommended to assign the drug to children under 14 years of age. To appoint a caution to patients with erosive-ulcerative lesions ZHKT in history. Against the backdrop of taking the medication may develop arrhythmias. In the course of treatment requires regular medical supervision. The composition of lipoproteins of blood should be monitored every 2-3 months. It should also control the function of the gall bladder, liver and pancreas, peripheral blood picture. At the same time klofibrat appointment strengthens the effects of indirect anticoagulants, should therefore reduce their initial dose in the treatment dose anticoagulants correcting according to the value of prothrombin time.

Lovastatin:

Shape of production: tablets.

What is Lovastatin:  Inhibits the synthesis of cholesterol in the liver at the stage mevalonovoy acid. Lowers cholesterol, TG, and LPNP LPONP blood; moderately increases the content of HDL, with antiaterogennym action.

Indications: giperlipoproteinemii not correcting a special diet and physical activity.
How should I take Lovastatin: initial dose - 10-20 mg 1 every day during the evening meal. If necessary, increase the dose of 1 every 4 weeks. The maximum daily dose - 80 mg, in 1 or 2 reception (during breakfast and dinner). In the case of reduction in plasma concentrations of total cholesterol to 140 mg/100 ml (3.6 mmol / l) or LPNP-cholesterol up to 75 mg/100 ml (1.94 mmol / L) dose of the drug should be reduced. At the same time appointing lovastatina and drugs that suppress the immune system, lovastatina daily dose should not exceed 20 mg.

Side effects Lovastatin: The drug is generally well tolerated. There may be nausea, diarrhea, constipation, flatulence, dry mouth, disturbance of taste, anorexia, increased levels of hepatic transaminases in the blood, transient increase of CFC in the blood, dizziness, headache, sleep disorders, convulsions, paresthesia. Rarely - mialgii, miopatii, hepatitis. In isolated cases, cholestatic jaundice, mental disturbances, rash, swelling Kvinke, toxic epidermal nekroliz, hemolytic anemia, leukopenia, thrombocytopenia.

What should I avoid while taking Lovastatin: acute liver disease, the constant increase of hepatic transaminases in the serum of unknown etiology, or the possibility of pregnancy, lactation, severe general condition of the patient’s hypersensitivity to the drug.

Cautions: Designate the drug with caution to patients with a history of liver disease, and patients who abuse alcohol. In the case of a persistent increase of hepatic transaminases in the blood and / or CFC is shown lifting the drug. Lovastatinom therapy should be interrupted for long periods or discontinued at the patient’s general condition due to an illness. In patients receiving both cyclosporin, gemfibrozil, or nicotinic acid, there have been cases rabdomioliza with subsequent development of acute renal failure.

Manufacturers: Mevakor (Mevacor) Merck Sharp & Dohme BV, The Netherlands; Medostatin (Medostatin) Medochemie, Cyprus; REKOL (RECOL) THEMIS CHEMICALS, India.

Pravastati:

Structure and Composition: 1 tablet contains sodium pravastatina 10 or 20 mg per pack 10 pcs.

Indications for use: the ineffectiveness of diet with hypercholesterolemia, hypercholesterolemia in combination with gipertriglitseridemiey.

Contraindications: hypersensitivity, aggravation of liver disease, nediagnostsirovannye persistent increase in liver function tests, age (under 18).

Adverse effects: mialgiya, miopatiya and rabdomioliz, increased activity of liver enzymes, rashes on the skin.

Cautions: Application of pregnancy and lactation: Contraindicated. If pregnancy occurs during the period of administration, reception should be discontinued.

Precautions: Gently used in patients with liver diseases in history, with alcohol abuse. Patients should be informed of the need for immediate treatment to the doctor when there is muscle pain, tenderness, or weakness (which may be due to inhibition reductase gidroksimetilglyutaril koenzima-A). Admission should be stopped with a substantial increase in the content and kreatinfosfokinazy suspected miopatiyu.

Simvastatin:

What is Simvastatin: simvastatin - this means the reduction of cholesterol content. He is the inhibitor of 3-hydroxy-3-methyl glutaril koenzima A (HMG-CoA) reductase, an enzyme involved in the formation of cholesterol in the liver. Simvastatin reduces the concentration of total cholesterol, low density lipoproteins cholesterol (LPNP) and triglycerides. Cholesterol content is very low density lipoproteins (LPONP) also decreases, while the cholesterol content of high density lipoproteins (HDL) is increased moderately. In addition simvastin has a number of other positive effects, including improved endothelial function (the inner layer of blood vessels), the drug also has antioxidant effect and inhibits the migration and proliferation of cells in the atherosclerotic process. Simvastatin also promotes gallstone dissolution. Simvastatin is presented in the form of an inactive lactones, which is relatively well absorbed from the gastrointestinal tract and converted into an active form of therapy. The first passage through the liver and metabolized delayed over 79% absorbed drug. It appears mainly with bile and faeces.
The therapeutic effect occurs within 2 weeks, the maximal effect observed after 4 - 6 weeks of treatment.

Indications for use: primary hypercholesterolemia type IIa and IIb. The drug is used as a monotherapy in cases where adherence to diet and other methods of treatment proved insufficient.
Coronary heart disease. The drug reduces the level of total cholesterol and low density lipoproteins cholesterol (LPNP) in patients with ischemic heart disease, and thus reduces the risk of myocardial infarction and death for these patients.

Contraindications: Hypersensitivity to any of the ingredients of the drug, liver disease in the active stage, or a sudden increasing persistent levels of serum transaminases, pregnancy and lactation, porphyria.

Warnings and precautions: simvastatinom treatment may cause improvement in liver enzymes or increased levels of transaminases. In most cases, this increase of small and clinically insignificant, but still recommended to determine the content of the liver enzymes in serum before treatment and regular monitoring during treatment. If the levels of transaminases in serum increased more than 3 times on top of standards, the treatment should be interrupted. Particular caution should be exercised when simvastatin designate patients that regularly consume large amounts of alcohol and / or liver diseases in history. Women of reproductive age who do not have a reliable contraceptive is not recommended Vazilip. Research the safety and effectiveness of simvastatina in children and adolescents under the age of 18 have not yet been carried out.
Simvastatin may cause increasing muscle enzyme kreatinkinazy usually clinically insignificant, but in rare cases can develop miopatiya. Miopatiya manifest as a significant increase in the content of this enzyme (more than 10 times on the normal rate), pain, stiffness and muscular weakness. In the most severe cases can develop rabdomioliz (disintegration of muscle tissue). This can lead to acute renal failure. The risk of developing miopatii higher for those patients who used simvastatin concurrently with drugs that increase levels of serum simvastatina or reinforcing their effects. The risk of developing miopatii also higher in patients with severe renal insufficiency. Should pay attention to the increased activity in the differential diagnosis kreatinfosfokinazy zagrudinnoy pain.

Pregnancy and lactation: the drug is contraindicated during pregnancy and lactation. Women of childbearing age may take simvastatin only in cases where the probability of pregnancy is excluded.

Effects on psycho-physical ability: simvastatin no effect on psychomotor ability while driving or using machinery.

Interaction with other drugs: the simultaneous appointment of simvastatina and cyclosporin, fibroevoy acid derivatives, niacin, erythromycin, clarithromycin, ketokonazola, itrakonazola and nefazodona may cause miopatiyu with rabdomiolizom and renal insufficiency. If you are receiving with ritonavir may increase the concentration levels simvastatina serum. The simultaneous appointment simvastatina and warfarin may enhance the effect last for coagulation of blood, increasing the risk of hemorrhage. Patients simultaneously receiving simvastatin and digoxin contents in serum digoxin may increase, so such patients should be observed accordingly.

Dosage and method of application: the initial dose in the treatment of hypercholesterolemia was 10 mg simvastatina 1 time per day. Depending on the desired effect may be dose uvelichina up to 40 mg. Adjustments to dose is not required for elderly patients and patients with weak or moderate renal insufficiency. The dose of 10 mg simvastatina relatively safe for patients after organ transplants receiving cyclosporin, but the increase in dose is not recommended. Application simvastatina in children and adolescents under 18 years are not recommended.

Overdosage: described several cases of overdose simvastatina; in patients not been any violation or special effects. The highest dose, adopted one patient was 450 mg. If overdose simvastatina should take common measures for such cases (to cause vomiting, activated charcoal to appoint, it is necessary to control the vital functions). It also should monitor liver function and kidney and kreatinkinazy levels in serum.

Adverse effects: the majority of patients is well tolerated simvastatin. Its side effects are usually poorly expressed and are transient in nature. May be marked constipation, nausea, flatulence, indigestion, pain in the abdomen, diarrhea, vomiting, headache, sleep disturbance and improve the content of the liver enzymes; less marked dizziness, feeling of tiredness, muscle weakness, pruritus, and alopecia. Very rarely (in some cases) can be observed on depression, peripheral neyropatiya, impotence, worsening renal function, proteinuria, cataract, dermatomiozit, skin rash and eczema. For the majority of side effects, a direct causal nexus of taking the medication has not been established. Significant, but very rare group of side effects caused by simvastatinom are muscle diseases (miopatiya), manifested as muscle pain and stiffness, as well as increased blood kreatinkinazy (muscle fraction). In very rare cases can develop rabdomioliz, which can lead to kidney failure. If there are violations of the muscular system, it should immediately inform the doctor. Also in case of any other changes that may be associated with the use of drugs should be reported to the doctor.

Storage :
Store at temperatures not above 30 ° C.
Keep out of reach of children.

Holiday preparation:
The product is allowed only on medical prescription.

Packing:
According to 7 tablets per blister.
28 tablets of 10 and 20 mg (4 blisters) in a carton.

Alcohol, Nicotine, Drugs

We did not accidentally put the heading “Alcohol, nicotine, drugs” in the “erectile dysfunction (impotence) as a collateral manifestation of drug therapy.” First, a number of these substances initially created as a drug, and chemical composition can be attributed to the relative for some medicine substances. Secondly, the mechanism of influence of these substances on erectile function in some cases very similar to the mechanism of action of conventional drugs.

However, unlike all the chapters, which describe the influence of drugs on the potency, in this section, we put the following selection:

If the background of the use of alcohol, nicotine and drugs you mark infringement potency, immediately stop taking alcohol, nicotine and drugs. No need to wait, as the impact will be irreversible. Save yourself for your favorite.

Alcohol:

Widely believed that small doses of alcohol lead to emancipation, which may increase the libido. However, excessive and chronic alcohol consumption usually leads to erectile dysfunction (impotence) - in the form of acute or chronic problems.

Most sedative effect of alcohol exceeds the effect of emancipation. Chronic alcoholics suffer from erectile dysfunction (impotence) in half the cases. The main complaints of patients are reducing the severity of orgasm, reduction in sexual excitability, slowing in the onset of ejaculation. Possible reasons for this are the influence of alcohol on pituitary-axis gipotalyamus with the development of Hypogonadism. Often, the reduction of testosterone.

Alcoholism is often accompanied by development polineyropatii leading to neurogenic erectile dysfunction (impotence).

With chronic abuse of alcohol affected the liver and reduces the effectiveness of estrogen metabolism. Additional expression can be ginekomastiya.

If the background of alcohol you mark infringement potency immediately to part with this habit. No need to wait, as the impact will be irreversible. Save yourself for life and loved.

Nicotine:

Nicotine is the most common factor samointoksikatsii. Numerous studies confirmed the influence of nicotine on the natural erectile function. In an equal age groups of smokers have erectile dysfunction (impotence) occurs in 2 times more likely than the nonsmokers.

It is believed that nicotine leads to a local spasm of the internal sramnoy artery (a. pudenda interna). In addition, smoking accelerates the development of atherosclerosis and vascular pathology.

If you smoke and have to observe the violation of potency, to immediately throw this preposterous habit. No need to wait, as the impact will be irreversible. Save yourself for an active life and loved.

Cannabis:

Widespread perception that marijuana improves sexual function. Indeed, in early use, as now spoken, soft drugs, there is increasing severity of orgasm, and even improving erectile function. There is, however, rely on this temporary improvement. With chronic use of marijuana inevitably develop erectile dysfunction (impotence). The main mechanisms of the influence of marijuana on the sexual activity is a decrease in testosterone.

Do not trust your friends, recommending boost their sexual activity tightening of marijuana. The use of “soft drugs”, neminumo lead to erectile dysfunction (impotence).

DIURETICS

Veroshpiron

Diuretics include (diuretic drugs) are drugs that are often appointed primarily for the treatment of uncomplicated hypertension. Naiblee often leads to erectile dysfunction diuretics such as acetazolamide, amiloride, chlorthalidone, indapamide, spironolactone and diuretics tiazidovye.

Effect of diuretic drugs on erectile function demonstrated in many studies, both in the form of self-treatment, and in addition to other drugs (most often in combination with beta-blockers, and metildopoy kaptoprilom). It is believed that the use of diuretics, reduced the blood flow through the penis, because reduced vascular resistance in other areas of the body, and more blood goes there, do not reach the reproductive organs. Nesovsem For understandable reasons, is also the reduction of libido (sex drive) and also disrupted the process of ejaculation.

Spironolactone, an aldosterone antagonists, are believed to hinder the binding of dihydrotestosterone to androgen receptors. This leads to the conversion of testosterone to estradiol. This in turn leads to serious problems with potency and ginekomastii. This is a side spironolactone for direct manifestation depends on the dose and runs after its repeal. The frequency of erectile dysfunction (impotence) when receiving spironolactone to 30%.

If a receiving diuretics (diuretic drugs) developed erectile dysfunction and you’re concerned, do not stop taking medication without consulting your doctor. Many antihypertensive drugs, and your doctor will be able to find a replacement, to change the dose or offer a combination with another drug or switch to the treatment drugs, which affect less than erectile function. These drugs include inhibitors of ACE, such as enalapril and CAPTOPRIL, calcium channel blockers (VERAPAMIL) and the selective alpha-1 blockers.